The shortfall thus determines whether the target set for 2026-2030 can be met, amid declining public contributions and at a time when half of daily births already benefit from protection linked to Gavi funding.
The warning concerns the alliance's ability to maintain protection for children in the poorest countries, as donor countries reduce their contributions.
A decline in vaccination coverage concretely means an increase in infant mortality.
Founded in 2000, Gavi is a public health organization. It helps the poorest countries buy vaccines.
One in two children born each day on the planet is protected against childhood diseases thanks to the alliance's funding.
Gavi has set a new target: to vaccinate nearly 500 million children between 2026 and 2030.
To achieve this ambition, nearly $1.5 billion is still lacking.
In recent years, donor countries have tended to reduce their funding to Gavi, with consequences for its work.
The alliance has therefore decided to turn more toward the private sector to raise the missing money, nearly $1.5 billion.